GENETIC CLUES TO WHY WE OVEREAT
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Scientists have discovered one likely reason some people eat to live and others live to eat.
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Researchers at the University at Buffalo in New York have found that people with genetically lower dopamine – a neurotransmitter that helps make activities and substances more rewarding – find food to be more rewarding than people without it. In other words, they are more motivated to eat, and they eat more.
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The findings, which appear in Behavioral Neuroscience, offer insights that could inspire treatment programmes for obesity, and maybe even genetically targeted drugs.
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Researchers measured the body mass of 29 obese adults and 45 who were not obese. They also swabbed DNA samples from inside their cheeks, had them fill in eating questionnaires and had them perform a series of tasks.
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Both obesity and the genetic make-up associated with fewer dopamine receptors predicted a significant response to food's rewarding power. Participants for whom food was most rewarding consumed more calories. What is more, obese participants clearly found food to be more rewarding than non-obese participants.
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